| Primary information |
|---|
| PRRID | PRRID_0599 |
| Ligand Name | Korean mistletoe lectin (KML-C) |
| Source | Korean mistletoe (Viscum album coloratum) (plant) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Lectin |
| Occurence | Natural |
| Role of Ligand | Binding leads to the upregulation of interleukin-1 receptor-associated kinase-1 (IRAK1), resulting in macrophage activation and TNF-a production. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Macropahges |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9QUK6.fasta |
| Swiss prot ID | Q9QUK6 |
| Length Of Receptor | 835 |
| Function | KML-C has strong immunomodulatory effects, such as immune cell activation and cytokine induction, which results in antitumor activities or protection from microbial infections. |
| Assay used | ELISA |
| PMID | 20450885 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0599 |
| Ligand Name | Korean mistletoe lectin (KML-C) |
| Source | Korean mistletoe (Viscum album coloratum) (plant) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Lectin |
| Occurence | Natural |
| Role of Ligand | Binding leads to the upregulation of interleukin-1 receptor-associated kinase-1 (IRAK1), resulting in macrophage activation and TNF-a production. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Macropahges |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9QUK6.fasta |
| Swiss prot ID | Q9QUK6 |
| Length Of Receptor | 835 |
| Function | KML-C has strong immunomodulatory effects, such as immune cell activation and cytokine induction, which results in antitumor activities or protection from microbial infections. |
| Assay used | ELISA |
| PMID | 20450885 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |