Detailed description page of PRRDB2.0

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PRRID_0590 details
Primary information
PRRIDPRRID_0590
Ligand NameIMO-4
SourceNA
Sequence of ligand5'-TCTGoToCG2TTAG-M-GATTG2CoToGTCT-5'
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandBinding leads to the secretion of cytokines and chemokines such as IL-6, IP-10, IL-12 and MCP-4
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationHEK293 cells, Bcells, PDCs, mDCs, PBMC
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionThis has immunostimulatory effect
Assay usedCytokines assay
PMID20381019
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0590
Ligand NameIMO-4
SourceNA
Sequence of ligand5'-TCTGoToCG2TTAG-M-GATTG2CoToGTCT-5'
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandBinding leads to the secretion of cytokines and chemokines such as IL-6, IP-10, IL-12 and MCP-4
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationHEK293 cells, Bcells, PDCs, mDCs, PBMC
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionThis has immunostimulatory effect
Assay usedCytokines assay
PMID20381019
Year of Publication2010
Pubchem assayPubchem Assay