Detailed description page of PRRDB2.0

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PRRID_0576 details
Primary information
PRRIDPRRID_0576
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandTheir binding leads to the enhanced production of type I IFNs, TNF-‚ç∫, IL-12 and driving a Th1 reponse pTTERN
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source NA
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionSuppresses angiogenesis and presents proapoptotic activity
Assay usedNA
PMID20636030
Year of Publication2010
Pubchem assayNA
Primary information
PRRIDPRRID_0576
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandTheir binding leads to the enhanced production of type I IFNs, TNF-‚ç∫, IL-12 and driving a Th1 reponse pTTERN
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source NA
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionSuppresses angiogenesis and presents proapoptotic activity
Assay usedNA
PMID20636030
Year of Publication2010
Pubchem assayNA