Detailed description page of PRRDB2.0

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PRRID_0561 details
Primary information
PRRIDPRRID_0561
Ligand NameHMGB1
SourceMouse model of endotoxemia
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of LigandActs as a mediator of inflammation and organ damage
Name of receptorRAGE
Type of receptorReceptor for advanced glycation endproducts (RAGE)
Source Mice
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ62151.fasta
Swiss prot IDQ62151
Length Of Receptor402
FunctionActs as a mediator of inflammation and organ damage
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0561
Ligand NameHMGB1
SourceMouse model of endotoxemia
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of LigandActs as a mediator of inflammation and organ damage
Name of receptorRAGE
Type of receptorReceptor for advanced glycation endproducts (RAGE)
Source Mice
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ62151.fasta
Swiss prot IDQ62151
Length Of Receptor402
FunctionActs as a mediator of inflammation and organ damage
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay