Detailed description page of PRRDB2.0

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PRRID_0559 details
Primary information
PRRIDPRRID_0559
Ligand NameHMGB1
SourceMouse model of endotoxemia
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of LigandActs as a mediator of inflammation and organ damage
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionActs as a mediator of inflammation and organ damage
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0559
Ligand NameHMGB1
SourceMouse model of endotoxemia
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of LigandActs as a mediator of inflammation and organ damage
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionActs as a mediator of inflammation and organ damage
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay