Primary information |
---|
PRRID | PRRID_0553 |
Ligand Name | Heme |
Source | Host (Endogenous) (others) |
Sequence of ligand | CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C)CCC(=O)O)CCC(=O)O |
Length | NA |
Type | Endogenous |
Occurence | Natural |
Role of Ligand | Binding of Heme to TLR4 leads to increased production of the proinflammatory cytokine, tumor necrosis factor-alpha |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | NA |
Localization | Macropahges |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | NA |
Assay used | NA |
PMID | 20689929 |
Year of Publication | 2010 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_0553 |
Ligand Name | Heme |
Source | Host (Endogenous) (others) |
Sequence of ligand | CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C)CCC(=O)O)CCC(=O)O |
Length | NA |
Type | Endogenous |
Occurence | Natural |
Role of Ligand | Binding of Heme to TLR4 leads to increased production of the proinflammatory cytokine, tumor necrosis factor-alpha |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | NA |
Localization | Macropahges |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | NA |
Assay used | NA |
PMID | 20689929 |
Year of Publication | 2010 |
Pubchem assay | NA |