Detailed description page of PRRDB2.0

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PRRID_0528 details
Primary information
PRRIDPRRID_0528
Ligand NameGardiquimod
Sourceimidazoquinoline (others)
Sequence of ligandCCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt activates the NF-
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
LocalizationSpleenocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
FunctionIt leads to the activation of splenocytes and the inhibition of murine B16 melanoma growth and metastasis
Assay usedNA
PMID20543857
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0528
Ligand NameGardiquimod
Sourceimidazoquinoline (others)
Sequence of ligandCCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt activates the NF-
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
LocalizationSpleenocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
FunctionIt leads to the activation of splenocytes and the inhibition of murine B16 melanoma growth and metastasis
Assay usedNA
PMID20543857
Year of Publication2010
Pubchem assayPubchem Assay