Detailed description page of PRRDB2.0

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PRRID_0525 details
Primary information
PRRIDPRRID_0525
Ligand NameFSL-1
SourceMycoplasma (Bacteria)
Sequence of ligandCCCCCCCCCCCCCCCC(=O)OCC(CSC[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCCN)C(=ON[C@@H(COC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of LigandFSL-1 binds to the heterocomplex of TLR2 and TLR6 and activates the downstream signalling
Name of receptorToll-like receptor 2/6 (TLR2/6)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationKeratinocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9BXR5.fasta
Swiss prot IDQ9BXR5
Length Of Receptor811
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20728939
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0525
Ligand NameFSL-1
SourceMycoplasma (Bacteria)
Sequence of ligandCCCCCCCCCCCCCCCC(=O)OCC(CSC[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCCN)C(=ON[C@@H(COC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of LigandFSL-1 binds to the heterocomplex of TLR2 and TLR6 and activates the downstream signalling
Name of receptorToll-like receptor 2/6 (TLR2/6)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationKeratinocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9BXR5.fasta
Swiss prot IDQ9BXR5
Length Of Receptor811
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20728939
Year of Publication2010
Pubchem assayPubchem Assay