Detailed description page of PRRDB2.0

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PRRID_0520 details
Primary information
PRRIDPRRID_0520
Ligand NameFlagellin (L94A)
SourcePseudomonas aeruginosa (Bacteria)
Sequence of ligandGLQIANRLTNQISGLNVATRNADDDISLAQTAEGVLQQATSILQRIRDLALQSANGSNSDVDRAALQKEVAAQQDELTRISDTTTFGGRKLLDGSFGTTSFQVGSNAYETIDISLQNASASAIGSYQVGSNGAGTVASVAGTATASGIASGTVNLVGGGQVKNIAIAAGDSAKAIAEKMDGAIPNLSARARTVFTADVSGVTGGSLNFDVTVGSNTVSLAGVTSTQDLADQLNSNSSKLGITASINDKGVLTITSATGENVKFGAQTGTATAGQVAVKVQGSDGKFEAAAKNVVAAGTAATTTVVTGYVQLNSPTAYSVSGTGTQASQVFGNASSSQKSSVASVDISTSDGAQNAIAVVDNVLAAIDAQRADLGAVQSRFKSTIDNLTNISENATNARSRIKDTDFAASETSALSNQVLQQAGTAILAQANQLP
Length434
TypeProtein
OccurenceNatural
Role of LigandIt elicits EGFR signaling in a TGF-a–related pathway, which leads to the secretion of cytokine/chemokine and production of antimicrobial peptides (AMPs).
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHuman corneal epithelial cells (HCECs)
DomainLRR
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt stimulates mucosal surface innate immune response.
Assay usedELISA
PMID20195469
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0520
Ligand NameFlagellin (L94A)
SourcePseudomonas aeruginosa (Bacteria)
Sequence of ligandGLQIANRLTNQISGLNVATRNADDDISLAQTAEGVLQQATSILQRIRDLALQSANGSNSDVDRAALQKEVAAQQDELTRISDTTTFGGRKLLDGSFGTTSFQVGSNAYETIDISLQNASASAIGSYQVGSNGAGTVASVAGTATASGIASGTVNLVGGGQVKNIAIAAGDSAKAIAEKMDGAIPNLSARARTVFTADVSGVTGGSLNFDVTVGSNTVSLAGVTSTQDLADQLNSNSSKLGITASINDKGVLTITSATGENVKFGAQTGTATAGQVAVKVQGSDGKFEAAAKNVVAAGTAATTTVVTGYVQLNSPTAYSVSGTGTQASQVFGNASSSQKSSVASVDISTSDGAQNAIAVVDNVLAAIDAQRADLGAVQSRFKSTIDNLTNISENATNARSRIKDTDFAASETSALSNQVLQQAGTAILAQANQLP
Length434
TypeProtein
OccurenceNatural
Role of LigandIt elicits EGFR signaling in a TGF-a–related pathway, which leads to the secretion of cytokine/chemokine and production of antimicrobial peptides (AMPs).
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHuman corneal epithelial cells (HCECs)
DomainLRR
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt stimulates mucosal surface innate immune response.
Assay usedELISA
PMID20195469
Year of Publication2010
Pubchem assayPubchem Assay