Detailed description page of PRRDB2.0

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PRRID_0509 details
Primary information
PRRIDPRRID_0509
Ligand NameFlagellin
SourceSalmonella typhimurium, Pseudomonas aeruginosa, Legionella pneumophila (Bacteria)
Sequence of ligandMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Length495
TypeProtein
OccurenceNatural
Role of LigandActivates Caspase-1, which results in the processing and release of the proinfl ammatory cytokines IL-1β and IL-18, leads to pathogen clearance and sepsis resistance.
Name of receptorIPAF
Type of receptorNOD-like receptor (NLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ15399.fasta
Swiss prot IDQ15399
Length Of Receptor786
FunctionIt results into pathogen clearance and sepsis resistance
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0509
Ligand NameFlagellin
SourceSalmonella typhimurium, Pseudomonas aeruginosa, Legionella pneumophila (Bacteria)
Sequence of ligandMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Length495
TypeProtein
OccurenceNatural
Role of LigandActivates Caspase-1, which results in the processing and release of the proinfl ammatory cytokines IL-1β and IL-18, leads to pathogen clearance and sepsis resistance.
Name of receptorIPAF
Type of receptorNOD-like receptor (NLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ15399.fasta
Swiss prot IDQ15399
Length Of Receptor786
FunctionIt results into pathogen clearance and sepsis resistance
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay