Detailed description page of PRRDB2.0

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PRRID_0500 details
Primary information
PRRIDPRRID_0500
Ligand NameF4 fimbriae
SourceEnterotoxigenic Escherichia coli (F4+ ETEC)
Sequence of ligandADWGPCRTASGDPFIFVTSFTKNIQNPTDNVTGQTYPDFYQWALGDKYSGVCECPSPNPTEARPTLYKTESTLAAGHNSTYFKITNNLEVSTRVYIANVGNVQVPFINKSNSQPGRECDQPTFGWTTGSKGQLSLYIAKPFVGEQNIPQTIIVSVFGTKKENVYSSVPISQVLLSGKVTVTQGCELAAGTSLDIDFGEYQAHDFKGRTGQPPQNVQKIQKELTFNCTNISDGVHIYLSLEGTPNAAYPSAISLGNADVGAVIEDGKGNILKPNDSNSLLEMNPGSLYEYVKRKVTTTITAYPVSTTGKLPAAGDYSGVATMHVELDGGGGGGGGGGATTDLGAKGTLKFSLKISQGHHHHHH
Length364
TypeProtein
OccurenceNatural
Role of LigandThe binding of ligand to TLR5 ETEC induce IL-6 and IL-8 cytokine secretion by intestinal cells
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Porcine
LocalizationIntestinal Epithelial Cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorC0L925.fasta
Swiss prot IDC0L925
Length Of Receptor844
FunctionIt induces proinflammatory responses in porcine intestinal epithelial cells
Assay usedQuantitative bacterial adherence assay
PMID20600278
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0500
Ligand NameF4 fimbriae
SourceEnterotoxigenic Escherichia coli (F4+ ETEC)
Sequence of ligandADWGPCRTASGDPFIFVTSFTKNIQNPTDNVTGQTYPDFYQWALGDKYSGVCECPSPNPTEARPTLYKTESTLAAGHNSTYFKITNNLEVSTRVYIANVGNVQVPFINKSNSQPGRECDQPTFGWTTGSKGQLSLYIAKPFVGEQNIPQTIIVSVFGTKKENVYSSVPISQVLLSGKVTVTQGCELAAGTSLDIDFGEYQAHDFKGRTGQPPQNVQKIQKELTFNCTNISDGVHIYLSLEGTPNAAYPSAISLGNADVGAVIEDGKGNILKPNDSNSLLEMNPGSLYEYVKRKVTTTITAYPVSTTGKLPAAGDYSGVATMHVELDGGGGGGGGGGATTDLGAKGTLKFSLKISQGHHHHHH
Length364
TypeProtein
OccurenceNatural
Role of LigandThe binding of ligand to TLR5 ETEC induce IL-6 and IL-8 cytokine secretion by intestinal cells
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Porcine
LocalizationIntestinal Epithelial Cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorC0L925.fasta
Swiss prot IDC0L925
Length Of Receptor844
FunctionIt induces proinflammatory responses in porcine intestinal epithelial cells
Assay usedQuantitative bacterial adherence assay
PMID20600278
Year of Publication2010
Pubchem assayPubchem Assay