Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_0498 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0498 |
| Ligand Name | extracellular ATP |
| Source | Injured cell (others) |
| Sequence of ligand | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O |
| Length | NA |
| Type | Endogenous |
| Occurence | Natural |
| Role of Ligand | It’s binding to the NLRP3 leads to the activation of caspase-1, which in result lead to the maturation of IL-1β |
| Name of receptor | Nod-like receptor P3 (NLRP3) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | NA |
| Localization | NA |
| Domain | NA |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | It activates the inflammasome via NLRP3 |
| Assay used | NA |
| PMID | 20303873 |
| Year of Publication | 2010 |
| Pubchem assay | NA |
| Primary information | |
|---|---|
| PRRID | PRRID_0498 |
| Ligand Name | extracellular ATP |
| Source | Injured cell (others) |
| Sequence of ligand | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O |
| Length | NA |
| Type | Endogenous |
| Occurence | Natural |
| Role of Ligand | It’s binding to the NLRP3 leads to the activation of caspase-1, which in result lead to the maturation of IL-1β |
| Name of receptor | Nod-like receptor P3 (NLRP3) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | NA |
| Localization | NA |
| Domain | NA |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | It activates the inflammasome via NLRP3 |
| Assay used | NA |
| PMID | 20303873 |
| Year of Publication | 2010 |
| Pubchem assay | NA |