Detailed description page of PRRDB2.0

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PRRID_0497 details
Primary information
PRRIDPRRID_0497
Ligand NameEprJ and EscI
SourceE. coli(Bacteria)
Sequence of ligandMSVSNMPPIDRAEQSTAHEIQQAKVIDLNDRVLNLDNPDDKMISAFANYAVQTENWQQNALQALRSDKEGLTPEKLLVLQDHVLNYNVEVSLVEH, MIYFLTDLIKFYCLMKLYEYKNIKIDLVLTEDIIPEDKLLEIIQSDDIVKLARKKTCEHLLRARRKSKKLKTESRKKIARKIMAMRERIRKNNKIKLEKEVNKSIKWVKDIQDIELVLMQDIMNKVHSSLTNALHSLDTSSRINWDDLLNEVVRETLSHNNIVGAIKITKNPDIKLDPGEANNIQLINDADAPLNKIIIENEYMRITLDPLEQINILLNSFKENYLSIIQE
Length95,231
TypeProtein
OccurenceNatural
Role of LigandIt activates caspase-1 through NLRC4 and secrete IL-1β
Name of receptorNod-like receptor C4 (NLRC4)
Type of receptorNOD-like receptor (NLR)
Source Mice
LocalizationBone marrow–derived macrophages
DomainNA
Sequence of ReceptorQ3UP24.fasta
Swiss prot IDQ3UP24
Length Of Receptor1024
FunctionIt leads to the clearance of the pathogen from the system
Assay usedELISA
PMID20133635
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0497
Ligand NameEprJ and EscI
SourceE. coli(Bacteria)
Sequence of ligandMSVSNMPPIDRAEQSTAHEIQQAKVIDLNDRVLNLDNPDDKMISAFANYAVQTENWQQNALQALRSDKEGLTPEKLLVLQDHVLNYNVEVSLVEH, MIYFLTDLIKFYCLMKLYEYKNIKIDLVLTEDIIPEDKLLEIIQSDDIVKLARKKTCEHLLRARRKSKKLKTESRKKIARKIMAMRERIRKNNKIKLEKEVNKSIKWVKDIQDIELVLMQDIMNKVHSSLTNALHSLDTSSRINWDDLLNEVVRETLSHNNIVGAIKITKNPDIKLDPGEANNIQLINDADAPLNKIIIENEYMRITLDPLEQINILLNSFKENYLSIIQE
Length95,231
TypeProtein
OccurenceNatural
Role of LigandIt activates caspase-1 through NLRC4 and secrete IL-1β
Name of receptorNod-like receptor C4 (NLRC4)
Type of receptorNOD-like receptor (NLR)
Source Mice
LocalizationBone marrow–derived macrophages
DomainNA
Sequence of ReceptorQ3UP24.fasta
Swiss prot IDQ3UP24
Length Of Receptor1024
FunctionIt leads to the clearance of the pathogen from the system
Assay usedELISA
PMID20133635
Year of Publication2010
Pubchem assayPubchem Assay