| Primary information |
|---|
| PRRID | PRRID_0456 |
| Ligand Name | CTPR-3 |
| Source | High 5 insect cells (others) |
| Sequence of ligand | MQVLELRNTLGSLDATDYASCLVRSLRADEKIWTFLTQSTGEINKQIADLAASQKLNPGTLGLLAFNQELLKSNFPDSRLQVSVLEECMVNYESFIQQHNAPATLEEAAKLAVVLIEKRKIAPAWRHTLLEVVNRMHLNDGKALRSVWGTAFTIIINLIKDRDEFLYDLLKLQSAEQGIESLIFAVISLPISENEKAEKLVKALQDQSAAIIEKTLSFIISINEKELAISAAQLLVGKYKIEEASEKGSKDILENLEASLQQSMLYKQIASVAQIAGDTDLASNLLEKSSAIFDAISTGIKIQNLSLLEQTANRLEFNEQVRKFQLDQANHPALAQEMASVGIVAQDQTQDELQSKPITAISQAKMINSAGNPELAKSECEKAFISIDHRTYDAAVEFVPQFNPNWNPGEMVNTLVELGAKKEALKMAASLYAKNPASLSAAQASAETYYESADYAAALPMFEYASMAGENSTPMLRQLADCYAQTGNSEACYKVRKQLVEVEAPVIPDLLQFADSAISAGRCNEVFPITSQIIKQDPMNASALTINGKAYAMTGNRDQALEFFSKAIEVGSDDADPWIGLSELQVKGGEFRQAIESLRQGLAALPADREIKRRLAEQLMDSGSASEALPLLNDLAEDDQNALIGVLQLDALKILGMPEYDAMVVSLYSKFPENEEIAQAFAAQLIKNGKHSEAKTVLQAKLSQVQSNTPTALTYAEAVVGMDVHYSGEPKSISAQEMEKVESIVDRYLEQDSDHTHAQLVKAELLVGKAKYAEAFKLYSRLLEKQTSVDKSLWERIQAGFAQSA |
| Length | 805 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | It act as LPS antagonist of the adipose tissue and induces the expression of p-p38 MAPK and p-ERK-2/-2 in adipocytes |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | 3T3-L1 preadipocytes |
| Localization | adipocytes |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9QUK6.fasta |
| Swiss prot ID | Q9QUK6 |
| Length Of Receptor | 835 |
| Function | It has the role in the inflammation. |
| Assay used | NA |
| PMID | 20739398 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0456 |
| Ligand Name | CTPR-3 |
| Source | High 5 insect cells (others) |
| Sequence of ligand | MQVLELRNTLGSLDATDYASCLVRSLRADEKIWTFLTQSTGEINKQIADLAASQKLNPGTLGLLAFNQELLKSNFPDSRLQVSVLEECMVNYESFIQQHNAPATLEEAAKLAVVLIEKRKIAPAWRHTLLEVVNRMHLNDGKALRSVWGTAFTIIINLIKDRDEFLYDLLKLQSAEQGIESLIFAVISLPISENEKAEKLVKALQDQSAAIIEKTLSFIISINEKELAISAAQLLVGKYKIEEASEKGSKDILENLEASLQQSMLYKQIASVAQIAGDTDLASNLLEKSSAIFDAISTGIKIQNLSLLEQTANRLEFNEQVRKFQLDQANHPALAQEMASVGIVAQDQTQDELQSKPITAISQAKMINSAGNPELAKSECEKAFISIDHRTYDAAVEFVPQFNPNWNPGEMVNTLVELGAKKEALKMAASLYAKNPASLSAAQASAETYYESADYAAALPMFEYASMAGENSTPMLRQLADCYAQTGNSEACYKVRKQLVEVEAPVIPDLLQFADSAISAGRCNEVFPITSQIIKQDPMNASALTINGKAYAMTGNRDQALEFFSKAIEVGSDDADPWIGLSELQVKGGEFRQAIESLRQGLAALPADREIKRRLAEQLMDSGSASEALPLLNDLAEDDQNALIGVLQLDALKILGMPEYDAMVVSLYSKFPENEEIAQAFAAQLIKNGKHSEAKTVLQAKLSQVQSNTPTALTYAEAVVGMDVHYSGEPKSISAQEMEKVESIVDRYLEQDSDHTHAQLVKAELLVGKAKYAEAFKLYSRLLEKQTSVDKSLWERIQAGFAQSA |
| Length | 805 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | It act as LPS antagonist of the adipose tissue and induces the expression of p-p38 MAPK and p-ERK-2/-2 in adipocytes |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | 3T3-L1 preadipocytes |
| Localization | adipocytes |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9QUK6.fasta |
| Swiss prot ID | Q9QUK6 |
| Length Of Receptor | 835 |
| Function | It has the role in the inflammation. |
| Assay used | NA |
| PMID | 20739398 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |