| Primary information |
|---|
| PRRID | PRRID_0426 |
| Ligand Name | Bacterial DNA |
| Source | Porphyromonas gingivalis and Tannerella forsythia (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | It induces the release of IL-8 , IL-1beta, IL-6 TNF-alpha, and NF- |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Monocytic cells (THP-1 cells) |
| Domain | LRR |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | Immune responses triggered by periodontal bacterial nucleic acids mediated by inducing proinflammatory cytokine production through the TLR9 signaling pathway. |
| Assay used | ELISA |
| PMID | 20331800 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0426 |
| Ligand Name | Bacterial DNA |
| Source | Porphyromonas gingivalis and Tannerella forsythia (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | It induces the release of IL-8 , IL-1beta, IL-6 TNF-alpha, and NF- |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Monocytic cells (THP-1 cells) |
| Domain | LRR |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | Immune responses triggered by periodontal bacterial nucleic acids mediated by inducing proinflammatory cytokine production through the TLR9 signaling pathway. |
| Assay used | ELISA |
| PMID | 20331800 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |