Detailed description page of PRRDB2.0

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PRRID_0412 details
Primary information
PRRIDPRRID_0412
Ligand NameArabinosylated lipoarabinomannan (Ara-LAM)
SourceMycobacterium tuberculosis (Bacteria)
Sequence of ligandNA
LengthNA
TypeGlycolipid
OccurenceNatural
Role of LigandIt triggers downstream signalling via MyD88, lead to the ativation of NF-
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Leishmania donovani infected Mice
Localizationmacropahge
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionThe immunoprophylactic role played by Ara-LAM in conferring protection against visceral leishmaniasis
Assay usedEMSA and ELISA
PMID20500089
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0412
Ligand NameArabinosylated lipoarabinomannan (Ara-LAM)
SourceMycobacterium tuberculosis (Bacteria)
Sequence of ligandNA
LengthNA
TypeGlycolipid
OccurenceNatural
Role of LigandIt triggers downstream signalling via MyD88, lead to the ativation of NF-
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Leishmania donovani infected Mice
Localizationmacropahge
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionThe immunoprophylactic role played by Ara-LAM in conferring protection against visceral leishmaniasis
Assay usedEMSA and ELISA
PMID20500089
Year of Publication2010
Pubchem assayPubchem Assay