Detailed description page of PRRDB2.0
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PRRID_0392 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0392 |
| Ligand Name | SIMRA Compound 4 |
| Source | NA |
| Sequence of ligand | 5'-U*GCU*GCUUGUG-X-GUGUUCGU*CGU*-5' |
| Length | 23 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | SIMRA compounds containing arabinonucleotides induces the cytokines production in human pDCs cultures such as IFN-γ, IFN-α, IL-12, TNF-α, MIP-1α, MIP-1β. |
| Name of receptor | Toll-like receptor 8 (TLR8) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | pDCs |
| Domain | NA |
| Sequence of Receptor | Q9NR97.fasta |
| Swiss prot ID | Q9NR97 |
| Length Of Receptor | 1041 |
| Function | This induces the inflammatory response. |
| Assay used | NA |
| PMID | 19269175 |
| Year of Publication | 2009 |
| Pubchem assay | Pubchem Assay |
| Primary information | |
|---|---|
| PRRID | PRRID_0392 |
| Ligand Name | SIMRA Compound 4 |
| Source | NA |
| Sequence of ligand | 5'-U*GCU*GCUUGUG-X-GUGUUCGU*CGU*-5' |
| Length | 23 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | SIMRA compounds containing arabinonucleotides induces the cytokines production in human pDCs cultures such as IFN-γ, IFN-α, IL-12, TNF-α, MIP-1α, MIP-1β. |
| Name of receptor | Toll-like receptor 8 (TLR8) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | pDCs |
| Domain | NA |
| Sequence of Receptor | Q9NR97.fasta |
| Swiss prot ID | Q9NR97 |
| Length Of Receptor | 1041 |
| Function | This induces the inflammatory response. |
| Assay used | NA |
| PMID | 19269175 |
| Year of Publication | 2009 |
| Pubchem assay | Pubchem Assay |