Detailed description page of PRRDB2.0

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PRRID_0380 details
Primary information
PRRIDPRRID_0380
Ligand NameSIMRA Compound 1
SourceNA
Sequence of ligand5'-UGCUGCUUGUG-X-GUGUUCGUCGU-5'
Length23
TypeNucleic Acid
OccurenceSynthetic
Role of LigandSIMRA compounds containing arabinonucleotides induced Th1-type cytokine/chemokine profiles in human PBMC cultures such as IL-1β, IL-2R, IL-8, IL-10, IL-12, IFN-α, IFN-γ, MCP-1, RANTES, MIP-1α, MIP-1β, TNF-α.
Name of receptorToll-like receptor 8 (TLR8)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationPBMCs
DomainNA
Sequence of ReceptorQ9NR97.fasta
Swiss prot IDQ9NR97
Length Of Receptor1041
FunctionThis induces the inflammatory response.
Assay usedPBMC assay
PMID19269175
Year of Publication2009
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0380
Ligand NameSIMRA Compound 1
SourceNA
Sequence of ligand5'-UGCUGCUUGUG-X-GUGUUCGUCGU-5'
Length23
TypeNucleic Acid
OccurenceSynthetic
Role of LigandSIMRA compounds containing arabinonucleotides induced Th1-type cytokine/chemokine profiles in human PBMC cultures such as IL-1β, IL-2R, IL-8, IL-10, IL-12, IFN-α, IFN-γ, MCP-1, RANTES, MIP-1α, MIP-1β, TNF-α.
Name of receptorToll-like receptor 8 (TLR8)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationPBMCs
DomainNA
Sequence of ReceptorQ9NR97.fasta
Swiss prot IDQ9NR97
Length Of Receptor1041
FunctionThis induces the inflammatory response.
Assay usedPBMC assay
PMID19269175
Year of Publication2009
Pubchem assayPubchem Assay