| Primary information |
|---|
| PRRID | PRRID_0379 |
| Ligand Name | SIMRA Compound 1 |
| Source | NA |
| Sequence of ligand | 5'-UGCUGCUUGUG-X-GUGUUCGUCGU-5' |
| Length | 23 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | Stminulation leads to the activation of NF-kappaB, leads to the release of proinflammatory cytokines |
| Name of receptor | Toll-like receptor 8 (TLR8) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | HEK293XL cells |
| Domain | NA |
| Sequence of Receptor | Q9NR97.fasta |
| Swiss prot ID | Q9NR97 |
| Length Of Receptor | 1041 |
| Function | This induces the inflammatory response. |
| Assay used | NA |
| PMID | 19269175 |
| Year of Publication | 2009 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0379 |
| Ligand Name | SIMRA Compound 1 |
| Source | NA |
| Sequence of ligand | 5'-UGCUGCUUGUG-X-GUGUUCGUCGU-5' |
| Length | 23 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | Stminulation leads to the activation of NF-kappaB, leads to the release of proinflammatory cytokines |
| Name of receptor | Toll-like receptor 8 (TLR8) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | HEK293XL cells |
| Domain | NA |
| Sequence of Receptor | Q9NR97.fasta |
| Swiss prot ID | Q9NR97 |
| Length Of Receptor | 1041 |
| Function | This induces the inflammatory response. |
| Assay used | NA |
| PMID | 19269175 |
| Year of Publication | 2009 |
| Pubchem assay | Pubchem Assay |