Detailed description page of PRRDB2.0

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PRRID_0376 details
Primary information
PRRIDPRRID_0376
Ligand NamePeptidoglycan (PGN)
SourceS. gordonii (Bacteria)
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of LigandStimulation elicits the production of tumour necrosis factor (TNF) and interleukin (IL)-6.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
LocalizationBone-marrow derived Dendritic cells
DomainLRR
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionThis activation can be attributed to multiple immunostimulatory components present within S. gordonii bacterial cells.
Assay usedELISA
PMID19284500
Year of Publication2009
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0376
Ligand NamePeptidoglycan (PGN)
SourceS. gordonii (Bacteria)
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of LigandStimulation elicits the production of tumour necrosis factor (TNF) and interleukin (IL)-6.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
LocalizationBone-marrow derived Dendritic cells
DomainLRR
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionThis activation can be attributed to multiple immunostimulatory components present within S. gordonii bacterial cells.
Assay usedELISA
PMID19284500
Year of Publication2009
Pubchem assayPubchem Assay