Detailed description page of PRRDB2.0

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PRRID_0375 details
Primary information
PRRIDPRRID_0375
Ligand NameMALP-2 (macrophage-activating lipopeptide 2)
SourceNA
Sequence of ligandC1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N
LengthNA
TypeLipopeptides
OccurenceNatural
Role of LigandMALP-2-induced degradation of I
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationlung epithelial cells (small airway lung epithelial (SALE))
DomainNA
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionThis induces the inflammatory response.
Assay usedNF-kappaB-luciferase reporter assays
PMID19265130
Year of Publication2009
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0375
Ligand NameMALP-2 (macrophage-activating lipopeptide 2)
SourceNA
Sequence of ligandC1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N
LengthNA
TypeLipopeptides
OccurenceNatural
Role of LigandMALP-2-induced degradation of I
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationlung epithelial cells (small airway lung epithelial (SALE))
DomainNA
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionThis induces the inflammatory response.
Assay usedNF-kappaB-luciferase reporter assays
PMID19265130
Year of Publication2009
Pubchem assayPubchem Assay