Detailed description page of PRRDB2.0

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PRRID_0350 details
Primary information
PRRIDPRRID_0350
Ligand NameT.g.HSP70
SourceT. gondii (others)
Sequence of ligandMGSSHHHHHHSSGLVPRGSHMLEMADSPAVGIDLGTTYSCVGVWKNDAVEIIANDQGNRTTPSYVAFTDTERLVGDAAKNQVARNPENTIFDAKRLIGRKFDDPSVQSDMKHWPFKVIAGPGDKPLIEVTYQGEKKTFHPEEVSAMVLGKMKEIAEAYLGKEVKEAVITVLAYFNDSQRQATKDAGTIAGLSVLRIINEPTAAAIAYGLDKKGCGEMNVLIFDMGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDFDNRLVDFCVQDFKRKNRGKDISTNSRALRRLRTQCERTKRTLSSSIQATIEIDSLFEGIDYSVSISRARFEELCMDYFRNSLLPVEKVLKDSGIDKRSVSEVVLVGGSTRIPKIQQLITDFFNGKEPCRSINPDEAVAYGAAVQAAILKGVTSSQVQDLLLLDVALLSLGLETAGGVMTKLIERNTTIPTKKSQTFTTYADNQPGVLIQVYEGERAMTKDNNLLGKFHLDGIPPAPRGVPQIEVTFDIDANGIMNVTAQDKSTGKSNQITITNDKGRLSASEIDRMVQEAEKYKAEDEQNKHRVEAKNGLENYCYHMRQTLDDEKLKDKISSEDRDTANKAIQEALDWLDKNQLAEKEEFEAKQKEVESVCTPIITKLYQAGAAAGGMPGGMGGMPGGMGGMPGGMGGMPGGMGSGC
Length674
TypeProtein
OccurenceNatural
Role of LigandIt leads to the activation of cytosolic phospholipase A2 and platelet-activating factor and activated the PAF production.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationSpleenocytes
DomainNA
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionIt induces the lethal anaphylactic reaction.
Assay usedNA
PMID18667035
Year of Publication2008
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0350
Ligand NameT.g.HSP70
SourceT. gondii (others)
Sequence of ligandMGSSHHHHHHSSGLVPRGSHMLEMADSPAVGIDLGTTYSCVGVWKNDAVEIIANDQGNRTTPSYVAFTDTERLVGDAAKNQVARNPENTIFDAKRLIGRKFDDPSVQSDMKHWPFKVIAGPGDKPLIEVTYQGEKKTFHPEEVSAMVLGKMKEIAEAYLGKEVKEAVITVLAYFNDSQRQATKDAGTIAGLSVLRIINEPTAAAIAYGLDKKGCGEMNVLIFDMGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDFDNRLVDFCVQDFKRKNRGKDISTNSRALRRLRTQCERTKRTLSSSIQATIEIDSLFEGIDYSVSISRARFEELCMDYFRNSLLPVEKVLKDSGIDKRSVSEVVLVGGSTRIPKIQQLITDFFNGKEPCRSINPDEAVAYGAAVQAAILKGVTSSQVQDLLLLDVALLSLGLETAGGVMTKLIERNTTIPTKKSQTFTTYADNQPGVLIQVYEGERAMTKDNNLLGKFHLDGIPPAPRGVPQIEVTFDIDANGIMNVTAQDKSTGKSNQITITNDKGRLSASEIDRMVQEAEKYKAEDEQNKHRVEAKNGLENYCYHMRQTLDDEKLKDKISSEDRDTANKAIQEALDWLDKNQLAEKEEFEAKQKEVESVCTPIITKLYQAGAAAGGMPGGMGGMPGGMGGMPGGMGGMPGGMGSGC
Length674
TypeProtein
OccurenceNatural
Role of LigandIt leads to the activation of cytosolic phospholipase A2 and platelet-activating factor and activated the PAF production.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationSpleenocytes
DomainNA
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionIt induces the lethal anaphylactic reaction.
Assay usedNA
PMID18667035
Year of Publication2008
Pubchem assayPubchem Assay