Detailed description page of PRRDB2.0

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PRRID_0321 details
Primary information
PRRIDPRRID_0321
Ligand NameLow Molecular Weight Hyaluronic Acid (LMW-HA)
SourceHost (Endogenous) (others)
Sequence of ligandCC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O
LengthNA
TypeGlycosaminoglycan
OccurenceNatural
Role of LigandIt leads to the production of antimicrobial peptide beta defensins 2.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationKeratinocytes NCTC 2544 cell line
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt leadsto the induction of an antibacterial response.
Assay usedELISA
PMID18641349
Year of Publication2008
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0321
Ligand NameLow Molecular Weight Hyaluronic Acid (LMW-HA)
SourceHost (Endogenous) (others)
Sequence of ligandCC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O
LengthNA
TypeGlycosaminoglycan
OccurenceNatural
Role of LigandIt leads to the production of antimicrobial peptide beta defensins 2.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationKeratinocytes NCTC 2544 cell line
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt leadsto the induction of an antibacterial response.
Assay usedELISA
PMID18641349
Year of Publication2008
Pubchem assayPubchem Assay