Detailed description page of PRRDB2.0

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PRRID_0308 details
Primary information
PRRIDPRRID_0308
Ligand NameLipopolysaccharide (LPS)
SourceBurkholderia pseudomallei(Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandStimulation via LPS leads to the activation of NF-KappaB, which resulted into the production of TNF-α, MIP-2, and IL-10.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHEK293 cells
DomainLRR
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt has a immunostimulatory role
Assay usedELISA
PMID18691413
Year of Publication2008
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0308
Ligand NameLipopolysaccharide (LPS)
SourceBurkholderia pseudomallei(Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandStimulation via LPS leads to the activation of NF-KappaB, which resulted into the production of TNF-α, MIP-2, and IL-10.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHEK293 cells
DomainLRR
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt has a immunostimulatory role
Assay usedELISA
PMID18691413
Year of Publication2008
Pubchem assayPubchem Assay