Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0298 details
Primary information
PRRIDPRRID_0298
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandimiquimod leads to decreased tyrosinase and MITF expression and is accompanied by decreased pigmentation.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMelanocytes
DomainNA
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
FunctionIt inhibits Melanogenesis and Proliferation of Human Melanocytes.
Assay usedNA
PMID18596825
Year of Publication2008
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0298
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandimiquimod leads to decreased tyrosinase and MITF expression and is accompanied by decreased pigmentation.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMelanocytes
DomainNA
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
FunctionIt inhibits Melanogenesis and Proliferation of Human Melanocytes.
Assay usedNA
PMID18596825
Year of Publication2008
Pubchem assayPubchem Assay