Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0296 details
Primary information
PRRIDPRRID_0296
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandUpon ligand engagement TLR proteins trigger downstream cellular signaling, leading to the activation of NF-
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Porcine
LocalizationLymph node tissue
DomainLRR
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt has a immunostimulatory role
Assay usedNF-
PMID18439678
Year of Publication2008
Pubchem assayNA
Primary information
PRRIDPRRID_0296
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandUpon ligand engagement TLR proteins trigger downstream cellular signaling, leading to the activation of NF-
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Porcine
LocalizationLymph node tissue
DomainLRR
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt has a immunostimulatory role
Assay usedNF-
PMID18439678
Year of Publication2008
Pubchem assayNA