| Primary information |
|---|
| PRRID | PRRID_0286 |
| Ligand Name | Flagellin |
| Source | Pseudomonas aeruginosa (Bacteria) |
| Sequence of ligand | GLQIANRLTNQISGLNVATRNADDDISLAQTAEGVLQQATSILQRIRDLALQSANGSNSDVDRAALQKEVAAQQDELTRISDTTTFGGRKLLDGSFGTTSFQVGSNAYETIDISLQNASASAIGSYQVGSNGAGTVASVAGTATASGIASGTVNLVGGGQVKNIAIAAGDSAKAIAEKMDGAIPNLSARARTVFTADVSGVTGGSLNFDVTVGSNTVSLAGVTSTQDLADQLNSNSSKLGITASINDKGVLTITSATGENVKFGAQTGTATAGQVAVKVQGSDGKFEAAAKNVVAAGTAATTTVVTGYVQLNSPTAYSVSGTGTQASQVFGNASSSQKSSVASVDISTSDGAQNAIAVVDNVLAAIDAQRADLGAVQSRFKSTIDNLTNISENATNARSRIKDTDFAASETSALSNQVLQQAGTAILAQANQLP |
| Length | 434 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | Stimulation demonstrated that TLR signaling appears to mediate the excessive cytokine production occurring in CF. |
| Name of receptor | Toll-like receptor 5 (TLR5) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | CF Patients |
| Localization | Airway epithelial cells and primary PBMCs |
| Domain | LRR |
| Sequence of Receptor | O60602.fasta |
| Swiss prot ID | O60602 |
| Length Of Receptor | 858 |
| Function | Stimultion of TLR5 leads to the excessive inflammation which leads to the damaginf effect. |
| Assay used | ELISA |
| PMID | 18490781 |
| Year of Publication | 2008 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0286 |
| Ligand Name | Flagellin |
| Source | Pseudomonas aeruginosa (Bacteria) |
| Sequence of ligand | GLQIANRLTNQISGLNVATRNADDDISLAQTAEGVLQQATSILQRIRDLALQSANGSNSDVDRAALQKEVAAQQDELTRISDTTTFGGRKLLDGSFGTTSFQVGSNAYETIDISLQNASASAIGSYQVGSNGAGTVASVAGTATASGIASGTVNLVGGGQVKNIAIAAGDSAKAIAEKMDGAIPNLSARARTVFTADVSGVTGGSLNFDVTVGSNTVSLAGVTSTQDLADQLNSNSSKLGITASINDKGVLTITSATGENVKFGAQTGTATAGQVAVKVQGSDGKFEAAAKNVVAAGTAATTTVVTGYVQLNSPTAYSVSGTGTQASQVFGNASSSQKSSVASVDISTSDGAQNAIAVVDNVLAAIDAQRADLGAVQSRFKSTIDNLTNISENATNARSRIKDTDFAASETSALSNQVLQQAGTAILAQANQLP |
| Length | 434 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | Stimulation demonstrated that TLR signaling appears to mediate the excessive cytokine production occurring in CF. |
| Name of receptor | Toll-like receptor 5 (TLR5) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | CF Patients |
| Localization | Airway epithelial cells and primary PBMCs |
| Domain | LRR |
| Sequence of Receptor | O60602.fasta |
| Swiss prot ID | O60602 |
| Length Of Receptor | 858 |
| Function | Stimultion of TLR5 leads to the excessive inflammation which leads to the damaginf effect. |
| Assay used | ELISA |
| PMID | 18490781 |
| Year of Publication | 2008 |
| Pubchem assay | Pubchem Assay |