| Primary information |
|---|
| PRRID | PRRID_0279 |
| Ligand Name | CpG2006 |
| Source | NA |
| Sequence of ligand | 5’-tcgtcgttttgtcgttttgtcgtt-3’ |
| Length | 24 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | Stimulation leads to the increased gene expression of cytokines and chemokines such as, IL-6, MIP1 alpha, MIP1 beta, TNF alpha, and LTA. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | B cells and pDC |
| Domain | NA |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | It induces changes in gene expression and protein production that effect B cell function such as, Cell Migration, Signal Transduction, Proliferation, Differentiation and Survival. |
| Assay used | ELISA |
| PMID | 18652679 |
| Year of Publication | 2008 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0279 |
| Ligand Name | CpG2006 |
| Source | NA |
| Sequence of ligand | 5’-tcgtcgttttgtcgttttgtcgtt-3’ |
| Length | 24 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | Stimulation leads to the increased gene expression of cytokines and chemokines such as, IL-6, MIP1 alpha, MIP1 beta, TNF alpha, and LTA. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | B cells and pDC |
| Domain | NA |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | It induces changes in gene expression and protein production that effect B cell function such as, Cell Migration, Signal Transduction, Proliferation, Differentiation and Survival. |
| Assay used | ELISA |
| PMID | 18652679 |
| Year of Publication | 2008 |
| Pubchem assay | Pubchem Assay |