| Role of Ligand | It has stimulated the production of interferon-‚ç∫ (IFN-‚ç∫), IFN-inducible protein-10 (IP-10), interleukin-1 receptor antagonist (IL-1Ra), monocyte chemotactic protein-1 (MCP-1), and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL),IL-12p70, IL-18, and IFN- |
| Primary information |
|---|
| PRRID | PRRID_0268 |
| Ligand Name | 852A |
| Source | NA |
| Sequence of ligand | CCCC=CC=CC(=O)NC(CC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(C1CCC(CC1)O)C(=O)NC(CCCN)C(=O)NC(C(C)O)C(=O)NC(C2CCC(CC2)O)C(=O)NC(C3CCC(CC3)O)C(=O)NC(C(C)O)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCN)C(=O)NC(C5CCC(CC5)O)C(=O)NC(C(C)O)C(=O)NC(C6CCC(CC6)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C7CCC(C(C7)Cl)O)C(=O)O |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | It has stimulated the production of interferon-‚ç∫ (IFN-‚ç∫), IFN-inducible protein-10 (IP-10), interleukin-1 receptor antagonist (IL-1Ra), monocyte chemotactic protein-1 (MCP-1), and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL),IL-12p70, IL-18, and IFN- |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Peripheral blood mononuclear cells (PBMC) |
| Domain | LRR |
| Sequence of Receptor | Q9NYK1.fasta |
| Swiss prot ID | Q9NYK1 |
| Length Of Receptor | 1049 |
| Function | It has inhibited the proliferation of tumor cell lines Hs294T and 769-P. |
| Assay used | ELISA |
| PMID | 18439103 |
| Year of Publication | 2008 |
| Pubchem assay | Pubchem Assay |