Detailed description page of PRRDB2.0

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PRRID_0218 details
Primary information
PRRIDPRRID_0218
Ligand NameBiglycan
SourceEndogenous (others)
Sequence of ligandMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT
Length238
TypeCarbohydrate
OccurenceNatural
Role of LigandImmunostimulant
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMacrophages
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
Functionsynthesis of TNF-alpha and MIP-2.
Assay usedWestern blotting and ELISA.
PMID16025156
Year of Publication2005
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0218
Ligand NameBiglycan
SourceEndogenous (others)
Sequence of ligandMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT
Length238
TypeCarbohydrate
OccurenceNatural
Role of LigandImmunostimulant
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMacrophages
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
Functionsynthesis of TNF-alpha and MIP-2.
Assay usedWestern blotting and ELISA.
PMID16025156
Year of Publication2005
Pubchem assayPubchem Assay