Detailed description page of PRRDB2.0

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PRRID_0217 details
Primary information
PRRIDPRRID_0217
Ligand NametGPI-mucin
SourceTrypanosoma (others)
Sequence of ligandMKWSALNMNEGRGQLNCFCDGYWLHFPWTNNPRDVRGSSFFCYFAFVLLCALHLLLCVCVPSVRGADTTDRSRRMCMRWSLVCRSCLHLPLPSMCWCCGRAVCVCVCVCLLPWIGVCVVRGVRRTVHAWLLPSPHVVCPLCVCLPHLSSPLLLSISLTVQISSTPLNDHTMMTTCRLLCALLVLALCCCPFLCVTATGTAKELNKADASAPSPPSNPPATTTGESGLQDVVSAAEPQDVDGDVRGTSGSETQSDGAADKSQKHDNNDTTGSQGSTNRSADQTDQNGEDPAATTTTTTTAPVAPSTTTTTEAPTTTTTRAPSRLREIDGSLSSSAWVCAPLLLAASALAYTTVG
Length353
TypeGlycoprotein
OccurenceNatural
Role of LigandIt induces the secretion of TNF-alpha and IL-12, which leads the production of cytokine IFN-gamma
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source NA
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt leads to the production of the IFN-gamma, which is a key cytokine in host resistance to infection with T. cruzi.
Assay usedNA
PMID15361229
Year of Publication2004
Pubchem assayNA
Primary information
PRRIDPRRID_0217
Ligand NametGPI-mucin
SourceTrypanosoma (others)
Sequence of ligandMKWSALNMNEGRGQLNCFCDGYWLHFPWTNNPRDVRGSSFFCYFAFVLLCALHLLLCVCVPSVRGADTTDRSRRMCMRWSLVCRSCLHLPLPSMCWCCGRAVCVCVCVCLLPWIGVCVVRGVRRTVHAWLLPSPHVVCPLCVCLPHLSSPLLLSISLTVQISSTPLNDHTMMTTCRLLCALLVLALCCCPFLCVTATGTAKELNKADASAPSPPSNPPATTTGESGLQDVVSAAEPQDVDGDVRGTSGSETQSDGAADKSQKHDNNDTTGSQGSTNRSADQTDQNGEDPAATTTTTTTAPVAPSTTTTTEAPTTTTTRAPSRLREIDGSLSSSAWVCAPLLLAASALAYTTVG
Length353
TypeGlycoprotein
OccurenceNatural
Role of LigandIt induces the secretion of TNF-alpha and IL-12, which leads the production of cytokine IFN-gamma
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source NA
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt leads to the production of the IFN-gamma, which is a key cytokine in host resistance to infection with T. cruzi.
Assay usedNA
PMID15361229
Year of Publication2004
Pubchem assayNA