| Primary information |
|---|
| PRRID | PRRID_0203 |
| Ligand Name | gp96 (GRP94) |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL |
| Length | 803 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | implicated in the pathophysiology of several autoimmune diseases |
| Name of receptor | Scavenger receptor class A |
| Type of receptor | Scavenger receptor (SR) |
| Source | C57BL/6 mice |
| Localization | Peritoneal macrophages |
| Domain | NA |
| Sequence of Receptor | Q08857.fasta |
| Swiss prot ID | Q08857 |
| Length Of Receptor | 472 |
| Function | play a substantial role in trafficking gp96 and calreticulin into macrophages, accounting for half of total receptor-mediated uptake |
| Assay used | NA |
| PMID | 15371419 |
| Year of Publication | 2004 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0203 |
| Ligand Name | gp96 (GRP94) |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL |
| Length | 803 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | implicated in the pathophysiology of several autoimmune diseases |
| Name of receptor | Scavenger receptor class A |
| Type of receptor | Scavenger receptor (SR) |
| Source | C57BL/6 mice |
| Localization | Peritoneal macrophages |
| Domain | NA |
| Sequence of Receptor | Q08857.fasta |
| Swiss prot ID | Q08857 |
| Length Of Receptor | 472 |
| Function | play a substantial role in trafficking gp96 and calreticulin into macrophages, accounting for half of total receptor-mediated uptake |
| Assay used | NA |
| PMID | 15371419 |
| Year of Publication | 2004 |
| Pubchem assay | Pubchem Assay |