Detailed description page of PRRDB2.0

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PRRID_0196 details
Primary information
PRRIDPRRID_0196
Ligand NamedsRNA
SourceNA
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt leads to the activation of NF-kappaB via TRIF adaptor molecule, which results into the secretion of the cytokines IL-8, IL-6, RANTES (regulated on activation normal T cell expressed and secreted), and interferon- and the up-regulation of the major adhesion molecule ICAM-1.
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationAlveolar and bronchial epithelial cells
DomainNA
Sequence of ReceptorO15455.fasta
Swiss prot IDO15455
Length Of Receptor904
FunctionIt causes pulmonary inflammation.
Assay usedELISA
PMID15579900
Year of Publication2004
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0196
Ligand NamedsRNA
SourceNA
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt leads to the activation of NF-kappaB via TRIF adaptor molecule, which results into the secretion of the cytokines IL-8, IL-6, RANTES (regulated on activation normal T cell expressed and secreted), and interferon- and the up-regulation of the major adhesion molecule ICAM-1.
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationAlveolar and bronchial epithelial cells
DomainNA
Sequence of ReceptorO15455.fasta
Swiss prot IDO15455
Length Of Receptor904
FunctionIt causes pulmonary inflammation.
Assay usedELISA
PMID15579900
Year of Publication2004
Pubchem assayPubchem Assay