Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_0150 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0150 |
| Ligand Name | 7-allyl-8-oxo-G (loxoribine) |
| Source | Guanosine (others) |
| Sequence of ligand | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | It induces the production of type I IFNs, tumor necrosis factor alpha and IL-12 |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Peripheral blood leukocytes |
| Domain | LRR |
| Sequence of Receptor | Q9NYK1.fasta |
| Swiss prot ID | Q9NYK1 |
| Length Of Receptor | 1049 |
| Function | It leads to the immunostimulatory by immune system. |
| Assay used | ELISA |
| PMID | 12738885 |
| Year of Publication | 2003 |
| Pubchem assay | Pubchem Assay |
| Primary information | |
|---|---|
| PRRID | PRRID_0150 |
| Ligand Name | 7-allyl-8-oxo-G (loxoribine) |
| Source | Guanosine (others) |
| Sequence of ligand | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | It induces the production of type I IFNs, tumor necrosis factor alpha and IL-12 |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Peripheral blood leukocytes |
| Domain | LRR |
| Sequence of Receptor | Q9NYK1.fasta |
| Swiss prot ID | Q9NYK1 |
| Length Of Receptor | 1049 |
| Function | It leads to the immunostimulatory by immune system. |
| Assay used | ELISA |
| PMID | 12738885 |
| Year of Publication | 2003 |
| Pubchem assay | Pubchem Assay |