Detailed description page of PRRDB2.0

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PRRID_0003 details
Primary information
PRRIDPRRID_0003
Ligand NameN(alpha)-acetylmuramyl-L-alanyl-D-isoglutaminyl-N(epsilon)-stearoyl'L'lysine (MDP-L ys-L18)
SourceMDP (others)
Sequence of ligandCCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceSynthetic
Role of LigandIt leads to the induction of interferon in the lung.
Name of receptorNucleotide Binding Oligomerization Domain Containing 2 (Nod2)
Type of receptorNOD-like receptor (NLR)
Source Sendai virus infected mice
LocalizationLungs
DomainNA
Sequence of ReceptorQ8K3Z0.fasta
Swiss prot IDQ8K3Z0
Length Of Receptor1020
FunctionIt augments host-resistance to viral infection.
Assay usedInterferon assay
PMID2417426
Year of Publication1985
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0003
Ligand NameN(alpha)-acetylmuramyl-L-alanyl-D-isoglutaminyl-N(epsilon)-stearoyl'L'lysine (MDP-L ys-L18)
SourceMDP (others)
Sequence of ligandCCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceSynthetic
Role of LigandIt leads to the induction of interferon in the lung.
Name of receptorNucleotide Binding Oligomerization Domain Containing 2 (Nod2)
Type of receptorNOD-like receptor (NLR)
Source Sendai virus infected mice
LocalizationLungs
DomainNA
Sequence of ReceptorQ8K3Z0.fasta
Swiss prot IDQ8K3Z0
Length Of Receptor1020
FunctionIt augments host-resistance to viral infection.
Assay usedInterferon assay
PMID2417426
Year of Publication1985
Pubchem assayPubchem Assay