The total number of records retrieved from this search are 2. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_1276	Virus nameHerpes simplex virus	Virus strainHSV-HF10	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationAttenuated strain of HSV	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismDBA/2 mice model isograft for M3 cell line	In-vivo virus concentration1.0E+6 pfu	In-vivo toxicityNA	In-vivo resultAll mice survived	Mode of deliveryIntraperoroneal	Pathway inducedNA	Immunogenic effectInduction of HSV antigen positive cells	Clinical trialNA	PMID18226503
IDOV_1277	Virus nameHerpes simplex virus	Virus strainHSV-HF10	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationAttenuated strain of HSV	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismDBA/2 mice model isograft for M3 cell line	In-vivo virus concentration1.0E+7 pfu	In-vivo toxicityNA	In-vivo resultSignificant reduction in tumor size on day 18 and complete reduction of tumor size in some mice	Mode of deliverySubcutaneous	Pathway inducedNA	Immunogenic effectInduction of HSV antigen positive cells	Clinical trialNA	PMID18226503