Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 8. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3060Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI50% cell viabilityNoNoNA No responseNANANANA31011628
OV_3061Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻³ MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3062Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3090Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI45% cell viabilityNoNoNA No responseNANANANA31011628
OV_3091Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻³ MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3092Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3109Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman bladder cancer cell lineSW780NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3110Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman bladder cancer cell lineSW780NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628