The total number of records retrieved from this search are 16. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2273	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	1 MOI	100% cell death after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2287	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	1 MOI	100% cell death after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2301	Vesicular stomatitis virus	VSV-p1-GFP	RNA	Rhabdoviridae	Insertion of P gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	1 MOI	100% cell death after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2315	Vesicular stomatitis virus	Sev-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	1 MOI	60% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2329	Vesicular stomatitis virus	RSV-GFP	RNA	Rhabdoviridae	Insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	1 MOI	80% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2343	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	0.01 MOI	100% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2357	Vesicular stomatitis virus	VSV-Delta-M51-GFP	RNA	Rhabdoviridae	Deletion of M51 gene and insertion of GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	0.01 MOI	2% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2371	Vesicular stomatitis virus	VSV-p1-GFP	RNA	Rhabdoviridae	Insertion of P gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	0.01 MOI	2% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2385	Vesicular stomatitis virus	Sev-GFP	RNA	Rhabdoviridae	Virus expressing GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	0.01 MOI	70% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_2399	Vesicular stomatitis virus	RSV-GFP	RNA	Rhabdoviridae	Virus expressing GFP gene	Yes	No	No	ATCC	Pancreatic ductal adeonocarcinoma cell line	SUIT-2	80% confluent monolayer	NA	MTT assay	0.01 MOI	100% cell survival after 5 days	No	No	NA	No response	NA	NA	Downregulation of IFN-Gamma	NA	22238308
OV_5558	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	Human pancreatic cell line	SUIT-2	1.0E+5 cells per well	NA	NA	1 MOI	Significant death of cancer cell line after 72 hours	No	No	NA	No response	NA	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5563	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	NA	Human pancreatic cell line	SUIT-2	1.0E+5 cells per well	NA	NA	1 MOI	Significant death of cancer cell line after 72 hours	No	No	NA	No response	NA	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5568	Sindbis virus	AR339	RNA	Togaviridae	None	No	Sindbis virus in combination with Reovirus	No	NA	Human pancreatic cell line	SUIT-2	1.0E+5 cells per well	NA	NA	1 MOI	Enhancer cytolytic effect in combination after 72 hours	No	No	NA	No response	NA	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5572	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	Human pancreatic cell line	SUIT-2	NA	NA	NA	NA	NA	Nude mice xenografted subcutaneously for SUIT-2	1.0E+6 pfu	NA	Tumor volume reduced to below 3.0 cm after 10 weeks	Intratumoral	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5573	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	NA	Human pancreatic cell line	SUIT-2	NA	NA	NA	NA	NA	Nude mice xenografted subcutaneously for SUIT-2	1.0E+6 pfu	NA	Tumor volume reduced to below 1.0 cm after 10 weeks	Intratumoral	Induction of apoptosis by virus infection	NA	NA	US7270812B2
OV_5574	Sindbis virus	AR339	RNA	Togaviridae	None	No	Sindbis virus in combination with Reovirus	No	NA	Human pancreatic cell line	SUIT-2	NA	NA	NA	NA	NA	Nude mice xenografted subcutaneously for SUIT-2	1.0E+6 pfu	NA	Tumor volume reduced to below 0.5 cm after 10 weeks	Intratumoral	Induction of apoptosis by virus infection	NA	NA	US7270812B2