Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5256Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay0.1 PFU100% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5257Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay0.33 PFU70% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5258Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay1 PFU15% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5259Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay3.3 PFU5% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5260Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay10 PFU7% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5261Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay33 PFU1% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5262Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineSTOSE4000 cells per wellNAAlamar blue assay100 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340