The total number of records retrieved from this search are 29. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1230	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1231	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1232	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	60% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1233	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	65% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1234	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1235	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	30% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1236	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	65% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1237	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	70% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1238	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1239	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1240	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	55% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1241	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	60% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1242	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1243	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1244	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	55% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1245	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	60% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1348	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1349	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1350	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_2590	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	SMMC7721	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_5052	Vaccinia virus	VG9	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	50% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5053	Vaccinia virus	VG9	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	1 MOI	35% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5054	Vaccinia virus	VG9	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	10 MOI	20% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5055	Vaccinia virus	VG9-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	50% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5056	Vaccinia virus	VG9-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	1 MOI	35% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5057	Vaccinia virus	VG9-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	10 MOI	22% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5058	Vaccinia virus	WR-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	50% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5059	Vaccinia virus	WR-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	1 MOI	35% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5060	Vaccinia virus	WR-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	SMMC7721	1.0E+4 cells per well	NA	MTT assay	10 MOI	21% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492