Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 35. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_927Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10 virus particle/cell70% cancer cell survival after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_928Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA100 virus particle/ cell80% cancer cell survival after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_929Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA1000 virus particle/ cell80% cancer cell survival after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_930Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10000 virus particle/ cellAll cancer cell survive after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_959Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10 virus particle/cell90% cancer cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_960Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA100 virus particle/ cell90% cancer cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_961Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA1000 virus particle/ cell60% cancer cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_962Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoAlabama-BirminghamNeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10000 virus particle/ cell20% cancer cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_991Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10 pfu/cell90% cell survival after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_992Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA100 pfu/cell90% cell survival after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_993Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA1000 pfu/cell80% cell survival after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_994Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10000 pfu/cell60% cell kills after 2 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_995Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10 pfu/cell90% cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_996Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA100 pfu/cell50% cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_997Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA1000 pfu/cell20% cell survival after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_998Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10000 pfu/cell100% cell kills after 4 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_999Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10 pfu/cell60% cell survival after 6 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1000Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA100 pfu/cell100% cell kills after 6 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1001Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA1000 pfu/cell100% cell kills after 6 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1002Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10000 pfu/cell100% cell kills after 6 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1003Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10 pfu/cell10% cell kills after 8 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1004Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA100 pfu/cell100% cell kills after 8 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1005Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA1000 pfu/cell100% cell kills after 8 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1006Herpes simplex virusHSV-1DNAHerpesviridaeMutant NV1066YesNoNoMediGene Inc. San Diego, CANeuroblastoma cell lineSK-N-SH4.0E+3 cells per wellNANA10000 pfu/cell100% cell kills after 8 daysNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15570577
OV_1772ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay0.001 MOI70% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_1773ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay0.01 MOI50% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_1774ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay0.1 MOI40% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_1775ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay1 MOI20% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_1776ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay5 MOI30% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_1777ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay10 MOI22% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_1778ParovirusH-1PVDNAParoviridaeNoneYesNoNoATCCHuman neuroblastoma cell lineSK-N-SH7.6E+3 cells per wellNAMTT assay50 MOI20% cell survivalNoNoNA No responseNACell cycle arrest at G2 phase and induction of apoptosis by virusNANA20087864
OV_4205Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement1 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4210Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement0.01 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4211Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement0.1 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4212Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement1 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056