Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 11. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2232	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	90% cell survival after day 1	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2233	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	60% cell survival after day 2	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2234	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	55% cell survival after day 3	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2235	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	40% cell survival after day 4	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2236	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	100% cell death after day 5	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2237	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	60% cell survival after day 1	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2238	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	40% cell survival after day 2	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2239	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	20% cell survival after day 3	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2240	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	10% cell survival after day 4	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2241	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	SK-BR-3	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	100% cell death after day 5	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_4320	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human breast adenocarcinoma	SK-BR-3	4000 cells per well	NA	MTT assay	10 pfu	89.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347