The total number of records retrieved from this search are 48. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_403	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_405	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	39% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_407	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	42% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_409	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_411	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_413	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_427	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	50% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_429	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	50% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_431	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	51% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_433	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_435	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_437	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human ovarian serous adenocarcinoma cell line	OVCAR3	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_843	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	OVCAR3	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_4716	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4717	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4718	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4719	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	75% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4720	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	50% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4731	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4732	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4733	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4734	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	40% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4735	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4746	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	1% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4747	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	1% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4748	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	1% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4749	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	1% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4750	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	1% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4759	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4760	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4761	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4762	Myxoma virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4771	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4772	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4773	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	50% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4774	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	25% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4783	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4784	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	80% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4785	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	80% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4786	Maraba virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	50% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_5176	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5177	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5178	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5179	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	20% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5180	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	80% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5181	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	10% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5612	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human ovarian sarcoma cell line	OVCAR3	80% confluency	NA	MTT assay	34 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5831	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human ovarian carcinoma cell line	OVCAR3	80% confluency	NA	NA	34 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578