The total number of records retrieved from this search are 12. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_402	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	110% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_404	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	118% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_406	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	98% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_408	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	78% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_410	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	30% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_412	Adenovirus	CRAd-IL24 (Ad5/3Δ24cmvIL24)	DNA	Adenoviridae	Viral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).	Yes	No	IL-24 gene incorporated in place of the deleted E3B region	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_426	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	0.4 MOI	110% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_428	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	1 MOI	130% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_430	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	4 MOI	116% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_432	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	11 MOI	100% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_434	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	33 MOI	50% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517
OV_436	Adenovirus	CRAd-ING4 (Ad5/3Δ24cmvING4)	DNA	Adenoviridae	Viral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) gene	Yes	No	No	ATCC	Human cervical squamous cell carcinoma cell line	OV-4	3.0E+5 to 5.0E+5 cells per well	Toxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cells	MTS-based Cell Proliferation Assay (Promega)	100 MOI	16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)	No	No	NA	No response	NA	NA	NA	NA	27349517