Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4246Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4247Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI80% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4248Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI35% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4249Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI100% cell killing after day 7NoNoNA No responseNANANANA26317644
OV_5916Measles viruswild typeRNAParamyxoviridaeMutated for SLAM bindingYesNoNoNAHuman lung cancer cell lineNCI-H441NANAWST-1 assay1 MOIComplete cell killing after 7 daysNoNoNA No responseNANANANAUS10335481