The total number of records retrieved from this search are 16. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_763	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	99% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_764	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	76% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_765	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	64% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_766	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	60% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_767	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	52% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_793	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	99% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_794	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	60% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_795	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	49% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_796	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	35% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_797	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	30% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_819	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	64% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_820	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 240 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	55% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_827	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_828	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 240 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	42% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_5542	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutatnt in TK gene and UL 24 gene	Yes	No	No	ATCC	Human medulloblastoma cell line	SNB40	NA	NA	NA	0.001 MOI	All cells was dead after 4 days	No	No	NA	No response	NA	NA	NA	NA	US6770274
OV_5543	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutatnt in TK gene and UL 24 gene	Yes	No	No	ATCC	Human medulloblastoma cell line	SNB40	NA	NA	NA	0.1 MOI	All cells was dead after 4 days	No	No	NA	No response	NA	NA	NA	NA	US6770274