The total number of records retrieved from this search are 7. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4981	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	78% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4982	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0026 mg/ml + cisplatin 0.0625	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	35% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4983	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0026 mg/ml + carboplatin 0.0625	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	22% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4990	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	1 VP per cell	100% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4991	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	80% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4992	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	100 VP per cell	60% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4993	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	1000 VP per cell	20% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512