Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4453Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4654000 to 5000 cells per wellNAMTS assay0.04 MOI45% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4457Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4654000 to 5000 cells per wellNAMTS assay0.11 MOI30% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4461Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4654000 to 5000 cells per wellNAMTS assay0.33 MOI20% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4465Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4654000 to 5000 cells per wellNAMTS assay1 MOI15% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4469Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4654000 to 5000 cells per wellNAMTS assay3 MOI10% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380