Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4456Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN14000 to 5000 cells per wellNAMTS assay0.04 MOI30% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4460Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN14000 to 5000 cells per wellNAMTS assay0.11 MOI20% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4464Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN14000 to 5000 cells per wellNAMTS assay0.33 MOI10% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4468Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN14000 to 5000 cells per wellNAMTS assay1 MOI5% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4472Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN14000 to 5000 cells per wellNAMTS assay3 MOI100% cell killing after 96 hoursNoNoNA No responseNANANANA26951380