The total number of records retrieved from this search are 14. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_955	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_956	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	75% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_957	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	75% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_958	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_987	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_988	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	75% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_989	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	75% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_990	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1090	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1091	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	Lan-5	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_4208	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	8 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4216	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	10 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4217	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	0.1 MOI	7 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4218	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	Dr. R.C. Seeger, LA	Human neuroblastoma cell line	Lan-5	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	6 % cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	Maximum increased expression of Bcl-2 and Bcl-xL expression	NA	26298056